One such technique is autologous chondrocyte implantation ( ACI ), which is useful for large, isolated intercondylar notch of the articular surface.
2.
A bone and cartilage paste derived from crushed plugs of the non-weight-bearing intercondylar notch can achieve pain relief, repair damaged tissue, and restore function.
3.
First, cartilage cells are extracted arthroscopically from the patient's healthy articular cartilage that is located in a non load-bearing area of either the intercondylar notch or the superior ridge of the femoral condyles.
4.
Paste grafting involves replacing damaged cartilage with autologous cartilage and cancellous bone from the intercondylar notch in the center of the knee that is first morselized into a paste ( typically with hydroxyapatite ) to better fill the defect and more successfully promote chondrocyte activity and cartilage formation.
5.
Differences between males and females identified as potential causes are the active muscular protection of the knee joint, the greater Q angle putting more medial torque on the knee joint, relative ligament laxity caused by differences in hormonal activity from estrogen and relaxin, intercondylar notch dimensions, and muscular strength.
6.
The patient s chondrocytes are removed arthroscopically from a non load-bearing area from either the intercondylar notch or the superior ridge of the medial or lateral femoral condyles . 10, 000 cells are harvested and grown in vitro for approximately six weeks until the population reaches 10-12 million cells.
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